Tottenham confirm Kane has a 'significant' ankle injury

Kane absence makes Tottenham tougher to beat – Siewert

Dele Alli was also in the wars, receiving a broken hand during the win over City.

Kane is likely to miss the rest of the season after suffering yet another ankle ligament injury, this time in a tackle on City's Fabian Delph, while Alli sustained a fractured hand that left him unable to face Huddersfield. "I'm more optimistic about him being available for Manchester City in the second leg", he said.

Pochettino will be without his top goalscorer Harry Kane for the rest of the season but Lucas Moura appears ready to step into his shoes after his fabulous display on Saturday.

Kane had previously missed six weeks of action after injuring the same ankle during a January 15 Premier League match against Manchester United.

"He was so upset after the game, it was a hard moment for him", Pochettino said.

The club is locked in a battle for a top-four finish and can scarcely afford any further slip ups during their final six Premier League fixtures.

"We have to make sure the players on the pitch have full energy".

The England global was substituted with an ankle injury after 58 minutes of his side's 1-0 win over Manchester City in the first leg of their quarter-final tie on Tuesday.

"It's true that now we can have an opinion that it was a challenge with not too much need for it", added Pochettino.

It would be a big blow to Spurs who - despite holding a slender advantage in the tie - are facing a Man City side who have been formidable at home all season long. We'll see. It was an accident.

Surgeon Mark Davies, a leading specialist at the London Foot and Ankle Centre who has operated on Premier League footballers, says that going under the knife could help restore the strength of Kane's ligament to what it was before his first injury.

Serge Aurier, Eric Dier and Erik Lamela are Tottenham's other confirmed absentees for the visit of relegated Huddersfield.

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